用锶替代钙对青蛙骨骼肌兴奋-收缩偶联的影响。
The effect of the replacement of calcium by strontium on excitation-contraction coupling in frog skeletal muscle.
作者信息
Edwards C, Lorković H, Weber A
出版信息
J Physiol. 1966 Oct;186(2):295-306. doi: 10.1113/jphysiol.1966.sp008035.
Abstract
- In frog skeletal muscle strontium can replace calcium in potassium contractures for 5 hr, though it is less effective than Ca. Sr can restore the responsiveness to K after it had been lost in the presence of Mn.2. Muscles refractory to caffeine following repeated exposure to it in the absence of Ca, recover in part following addition of Sr.3. The uptake of (85)Sr was increased during mechanical activity, whereas the uptake of (58)Co was not changed. Resting uptake of (58)Co was 3-4 times greater than that of (85)Sr.4. Sr fully activated the myofibrillar adenosine triphosphatase (ATP-ase), though its affinity was about 30 times less than Ca.5. The sarcoplasmic reticulum took up Sr, though less effectively than Ca.
摘要
- 在青蛙骨骼肌中，锶可在钾挛缩过程中替代钙达5小时，尽管其效果不如钙。在存在锰的情况下失去对钾的反应性后，锶可恢复这种反应性。2. 在无钙条件下反复接触咖啡因后对其产生耐受的肌肉，添加锶后部分恢复。3. 机械活动期间（85）锶的摄取增加，而（58）钴的摄取未改变。（58）钴的静息摄取量比（85）锶大3 - 4倍。4. 锶可完全激活肌原纤维腺苷三磷酸酶（ATP酶），尽管其亲和力约比钙小30倍。5. 肌浆网摄取锶，尽管其效率低于钙。
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J Gen Physiol. 1965 May;48(5):841-58. doi: 10.1085/jgp.48.5.841.
2
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J Biol Chem. 1964 Feb;239:648-58.
3
4
THE ROLE OF RESTING POTENTIAL CHANGES IN THE CONTRACTILE FAILURE OF FROG SARTORIUS MUSCLES DURING CALCIUM DEPRIVATION.静息电位变化在缺钙期间青蛙缝匠肌收缩功能衰竭中的作用
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5
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7
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