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用高压液相色谱法定量测定市售防腐溶液中的己基间苯二酚。

Quantitative determination of hexylresorcinol in commercial antiseptic solution by high-pressure liquid chromatography.

作者信息

Musto J D, Sane J N, Warner V D

出版信息

J Pharm Sci. 1979 Feb;68(2):240-1. doi: 10.1002/jps.2600680232.

DOI:10.1002/jps.2600680232
PMID:423099
Abstract

High-pressure liquid chromatography was used with a 5-micron silica gel column to quantitate hexylresorcinol in a commercial antiseptic solution following extraction with methylene chloride. This method shows linearity to at least 0.025% hexylresorcinol. A mobile phase consisting of 63% heptane, 34% chloroform, and 5% methanol was used with a UV detector (254 nm) and a flow of 3 ml/min. No interfering substances were observed.

摘要

使用配备5微米硅胶柱的高压液相色谱法,在二氯甲烷萃取后,对一种市售防腐剂溶液中的己基间苯二酚进行定量。该方法对至少0.025%的己基间苯二酚显示出线性关系。使用由63%庚烷、34%氯仿和5%甲醇组成的流动相,搭配紫外检测器(254纳米),流速为3毫升/分钟。未观察到干扰物质。

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