Komarov F I, Ol'binskaia L I, Gorbatenko V P, Alekseevskikh Iv G, Antonenko N I
Kardiologiia. 1979 Feb;19(2):48-54.
The state of pulmonary hemodynamics and the contractile function of the right parts of the heart were studied clinically and instrumentally in 35 patients with diffuse chronic pathological conditions of the liver. The lungs and heart were examined morphologically in 24 persons who had died from cirrhosis of the liver in the edematous-ascitic stage. Pulmonary hypertension was found to be directly dependent on the degree of the diffuse affection of the liver. Secondary-compensatory changes in the contractile function of the myocardium of the right parts of the heart in response to increase of pressure in the pulmonary artery in patients with cirrhosis of the liver were proved to occur.
对35例患有肝脏弥漫性慢性病理状况的患者进行了临床和仪器检查,研究了其肺血流动力学状态和心脏右部的收缩功能。对24例死于水肿腹水期肝硬化的患者进行了肺和心脏的形态学检查。发现肺动脉高压与肝脏弥漫性病变程度直接相关。已证实,肝硬化患者的肺动脉压力升高会导致心脏右部心肌收缩功能发生继发性代偿性变化。