Guilmet D, Bachet J, Goudot B, Laurian C, Gigou F, Bical O, Barbagelatta M
J Thorac Cardiovasc Surg. 1979 Apr;77(4):516-21.
Use of a biological glue (GRF) is common in certain fields such as hepatic or renal surgery, but its use in vascular surgery, especially in acute aortic dissection, has not yet been reported. Our experience has demonstrated many advantages: The glue is very simple and safe to use. The aortic tissues are firmly reinforced and the sutures tighten immediately. The proximal aortic stump is anatomically reconstructed, and generally the aortic valve can be preserved and coronary reimplantation avoided. The preoperative and postoperative bleeding rates are low and the postoperative course generally is simple. The risk of maintenance or recurrence of the dissection process is reduced. Consequently, the hospital mortality rate can be reduced to about 10 percent and the long-term survival rate greatly improved.
生物胶水（GRF）在肝脏或肾脏手术等某些领域的使用很常见，但它在血管手术中的应用，尤其是在急性主动脉夹层手术中的应用尚未见报道。我们的经验显示出许多优点：这种胶水使用非常简单且安全。主动脉组织得到牢固加强，缝线立即收紧。主动脉近端残端在解剖学上得以重建，并且一般来说主动脉瓣能够得以保留，避免了冠状动脉再植入。术前和术后出血率低，术后病程通常较为简单。夹层过程持续或复发的风险降低。因此，医院死亡率可降至约10%，长期生存率大幅提高。
