Shingleton H M, Younger J B, Beasley W E, Levy D, Gore H, Lawrence W D
Obstet Gynecol. 1979 Mar;53(3 Suppl):92S-97S.
Adenocarcinoma of the vagina is an uncommon tumor. Many theories have been postulated for its etiology and tissue origin. Its occurrence in young women exposed in utero to diethylstilbestrol has pointed to estrogen influence as a possible etiologic factor. A case of adenocarcinoma of the vagina in a patient with gonadal dysgenesis is presented, and histologic and electron-microscopic observations are discussed. This patient is unique in that development of the vaginal neoplasm occurred in the absence of estrogen influence.
阴道腺癌是一种罕见的肿瘤。关于其病因和组织起源有许多假说。在子宫内接触己烯雌酚的年轻女性中发生该病,提示雌激素影响可能是一个病因。本文报告了一例性腺发育不全患者的阴道腺癌病例,并讨论了组织学和电子显微镜观察结果。该患者的独特之处在于阴道肿瘤是在没有雌激素影响的情况下发生的。