细胞外基质在伤口收缩中的作用。
The role of the ground substance in wound contraction.
作者信息
Jacques J
出版信息
Br J Exp Pathol. 1969 Oct;50(5):490-3.
Abstract
Excised skin wounds in rodents heal largely by contraction. The mechanism of this is disputed but it would appear to be the result of an inward pull on the skin edges by a force generated in the granulation tissue. Using a technique for demonstrating acid mucopolysaccharides on electron microscopy a change has been described in the organisation of the newly formed extracellular components in wounds, which suggests that contraction may result from the physico-chemical arrangement of these. This and other theories about contraction are discussed.
摘要
啮齿动物的切除皮肤伤口主要通过收缩愈合。其机制存在争议，但似乎是肉芽组织产生的力对皮肤边缘向内牵拉的结果。利用一种在电子显微镜下显示酸性粘多糖的技术，已描述了伤口中新形成的细胞外成分组织的变化，这表明收缩可能是这些成分物理化学排列的结果。本文讨论了这一理论以及其他关于收缩的理论。
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本文引用的文献
1
Studies in Wound Healing: II. The Role of Granulation Tissue in Contraction.伤口愈合研究：II. 肉芽组织在收缩中的作用。
Ann Surg. 1958 Aug;148(2):153-60. doi: 10.1097/00000658-195808000-00002.
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Contracture and intussusceptive growth in the healing of extensive wounds in mammalian skin.哺乳动物皮肤大面积伤口愈合过程中的挛缩与套叠式生长
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Contraction of full thickness skin wounds in the rat.大鼠全层皮肤伤口的收缩情况。
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Br J Surg. 1956 Mar;43(181):525-50. doi: 10.1002/bjs.18004318115.
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An electron-microscope study of acid mucopolysaccharide in rheumatic heart lesions.风湿性心脏病变中酸性粘多糖的电子显微镜研究。
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