Brill P W, Winchester P, Krauss A N, Symchych P
Radiology. 1979 Apr;131(1):83-7. doi: 10.1148/131.1.83.
Neonatal osteomyelitis presents with few clinical signs despite multiple sites of involvement. Four cases of osteomyelitis due to Staphylococcus aureus or Candida albicans were encountered in a neonatal intensive care unit. Three were unsuspected clinically and were detected as incidental radiologic findings. The fourth presented with soft-tissue abscesses. Long bone metaphyses were most frequently affected. Other sites included iliac bones, clavicles, and spine. On follow-up the bones healed, but one patient was left with hip deformity secondary to destruction of the cartilaginous femoral heads and another patient developed obstructive hydrocephalus due to Candida ventriculitis. Complete skeletal survey is indicated in any infant with osteomyelitis at one site to seek additional silent areas of involvement.
尽管有多个受累部位，但新生儿骨髓炎的临床症状却很少。在一个新生儿重症监护病房中，遇到了4例由金黄色葡萄球菌或白色念珠菌引起的骨髓炎病例。其中3例临床上未被怀疑，是在偶然的影像学检查中发现的。第4例表现为软组织脓肿。长骨的干骺端最常受累。其他部位包括髂骨、锁骨和脊柱。随访时，骨骼愈合，但1例患者因股骨头软骨破坏而遗留髋关节畸形，另1例患者因念珠菌性脑室炎而发生梗阻性脑积水。对于任何一处发生骨髓炎的婴儿，均应进行完整的骨骼检查，以寻找其他隐匿的受累部位。
