Basrur P K, Kanagawa H, Podliachouk L
Can J Comp Med. 1970 Oct;34(4):294-8.
An intersex horse exhibiting cell types of different sex chromosome constitution was subjected to further studies in order to determine whether the house was a mosaic or a chimera. Cultures of gonadal tissue and peripheral blood revealed mainly 64/XX and 64/XY cells, the former predominating in both tissues. The frequency of drumstick-bearing poly-morphonuclear neutrophils in the intersex horse was similar to that noted in normal mares. Blood type analysis using 17 naturally occurring agglutinins and hemolysins revealed partial agglutinations with three antibodies for the factors of the A system (anti-A, anti-F, and anti-I), and partial hemolysis with anti-Fr(3) suggesting erythrocyte chimerism probably resulting from intrauterine interchange of blood cell precursors as noted in other domestic animals. On the other hand, the presence of XX and XY cells in cultures of gonads which in our intersex horse were apparently devoid of germ cells, would seem to indicate wholebody chimerism resulting from double fertilization or blastocyst fusion.
一匹具有不同性染色体组成细胞类型的雌雄间性马接受了进一步研究，以确定这匹马是嵌合体还是奇美拉。性腺组织和外周血培养物主要显示出64/XX和64/XY细胞，前者在两种组织中均占主导。雌雄间性马中带有鼓槌的多形核中性粒细胞的频率与正常母马中观察到的相似。使用17种天然存在的凝集素和溶血素进行血型分析，发现与A系统因子的三种抗体（抗A、抗F和抗I）发生部分凝集，与抗Fr(3)发生部分溶血，这表明红细胞嵌合现象可能是由于子宫内血细胞前体的交换所致，正如在其他家畜中所观察到的那样。另一方面，在我们这匹雌雄间性马的性腺培养物中存在XX和XY细胞，而这些性腺显然没有生殖细胞，这似乎表明是由双受精或胚泡融合导致的全身嵌合现象。
