Walker F, Carter J, Crawford G P, Laird H, Lessells A M, Pollet J E
Br J Exp Pathol. 1970 Aug;51(4):379-84.
The immunological privilege of the hamster cheek pouch has been attributed to properties of its areolar connective tissue. This tissue was investigated using a range of biochemical, histochemical and immunological procedures. An unusual feature of the tissue is the presence of an, as yet incompletely characterized, acidic mucosubstance of mast cell origin. Also present are heparin and probably keratan sulphate. Attention is drawn to the highly sulphated mucopolysaccharides as possible agents which can prevent immunological recognition.
仓鼠颊囊的免疫赦免归因于其疏松结缔组织的特性。使用一系列生化、组织化学和免疫学方法对该组织进行了研究。该组织的一个不寻常特征是存在一种源自肥大细胞的酸性粘多糖物质,其特征尚未完全明确。此外还存在肝素以及可能的硫酸角质素。人们注意到高度硫酸化的粘多糖可能是能够阻止免疫识别的介质。