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仓鼠颊囊黏膜物质与免疫赦免

Hamster cheek pouch mucosubstances and immunological privilege.

作者信息

Walker F, Carter J, Crawford G P, Laird H, Lessells A M, Pollet J E

出版信息

Br J Exp Pathol. 1970 Aug;51(4):379-84.

PMID:4249592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2072312/
Abstract

The immunological privilege of the hamster cheek pouch has been attributed to properties of its areolar connective tissue. This tissue was investigated using a range of biochemical, histochemical and immunological procedures. An unusual feature of the tissue is the presence of an, as yet incompletely characterized, acidic mucosubstance of mast cell origin. Also present are heparin and probably keratan sulphate. Attention is drawn to the highly sulphated mucopolysaccharides as possible agents which can prevent immunological recognition.

摘要

仓鼠颊囊的免疫赦免归因于其疏松结缔组织的特性。使用一系列生化、组织化学和免疫学方法对该组织进行了研究。该组织的一个不寻常特征是存在一种源自肥大细胞的酸性粘多糖物质，其特征尚未完全明确。此外还存在肝素以及可能的硫酸角质素。人们注意到高度硫酸化的粘多糖可能是能够阻止免疫识别的介质。

相似文献

1
Hamster cheek pouch mucosubstances and immunological privilege.仓鼠颊囊黏膜物质与免疫赦免
Br J Exp Pathol. 1970 Aug;51(4):379-84.
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Fluorescence histochemical investigations of connective tissue. 3. Fluorescence histochemistry of the heparin content of mast cells.结缔组织的荧光组织化学研究。3. 肥大细胞肝素含量的荧光组织化学
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Initial lymphatics are present in the loose areolar connective tissue of the golden hamster's cheek pouch.初始淋巴管存在于金黄地鼠颊囊的疏松结缔组织中。
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Periarteriolar localization of mast cells promotes oriented interstitial migration of leukocytes in the hamster cheek pouch.肥大细胞在小动脉周围的定位促进了白细胞在仓鼠颊囊内的定向间质迁移。
Am J Pathol. 1989 Jan;134(1):161-9.
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Mast cells and tissue water: studies on living connective tissue in the hamster cheek pouch.肥大细胞与组织液：对仓鼠颊囊活体结缔组织的研究
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[Intravitalmicroscopic observations of the cheek pouch in the hamster after implantation of teflon paste (author's transl)].[植入聚四氟乙烯糊剂后对仓鼠颊囊的活体显微镜观察（作者译）]
Z Laryngol Rhinol Otol. 1973 Nov;52(11):837-40.
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Hormonal effects on mast cells; studies on living connective tissue in the hamster cheek pouch.激素对肥大细胞的影响；对仓鼠颊囊活体结缔组织的研究。
Acta Endocrinol (Copenh). 1956 Jun;22(2):157-65. doi: 10.1530/acta.0.0220157.

本文引用的文献

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A submicrodetermination of glucose.葡萄糖的亚微量测定
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A method for the separation of acid mucopolysaccharides: its application to the isolation of heparin from the skin of rats.一种酸性粘多糖的分离方法：其在从大鼠皮肤中分离肝素的应用。
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Induction of immunological tolerance by porcine liver allografts.猪肝同种异体移植诱导免疫耐受
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6
Surface mucin of human trophoblast.人滋养层细胞的表面黏蛋白
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7
Differential staining of acid glycosaminoglycans (mucopolysaccharides) by alcian blue in salt solutions.盐溶液中阿尔辛蓝对酸性糖胺聚糖（黏多糖）的鉴别染色
Histochemie. 1965 Oct 1;5(3):221-33. doi: 10.1007/BF00306130.
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"Critical electrolyte concentration" method in histochemistry.组织化学中的“临界电解质浓度”法
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9
A simple method for histochemical indentification of acid mucopolysaccharides in cryostat sections.一种在低温恒温器切片中对酸性粘多糖进行组织化学鉴定的简单方法。
Tohoku J Exp Med. 1968 Apr;94(4):385-91. doi: 10.1620/tjem.94.385.

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