南威尔士的乳腺良性与恶性疾病：尿甾体类激素研究
Benign and malignant breast disease in South Wales: a study of urinary steroids.
作者信息
Cameron E H, Griffiths K, Gleave E, Stewart H J, Forrest A P, Campbell H
出版信息
Br Med J. 1970 Dec 26;4(5738):768-71. doi: 10.1136/bmj.4.5738.768.
Abstract
The levels of aetiocholanolone, androsterone, and 17-hydroxycorticosteroids were measured in women without known disease of the breast, in women with benign breast disease, and in women with primary and advanced breast cancer. Statistical analysis showed there was no difference in the excretion of urinary 17-hydroxycorticosteroids in the various groups of patients. Detailed analysis of the aetiocholanolone and androsterone levels, however, indicated that patients with advanced localized disease excreted significantly less of these 11-deoxy-17-oxosteroids than those in the other groups.
摘要
对无已知乳腺疾病的女性、患有良性乳腺疾病的女性以及患有原发性和晚期乳腺癌的女性，测定了本胆烷醇酮、雄酮和17 - 羟皮质类固醇的水平。统计分析表明，各组患者尿中17 - 羟皮质类固醇的排泄量没有差异。然而，对本胆烷醇酮和雄酮水平的详细分析表明，晚期局限性疾病患者排泄的这些11 - 脱氧 - 17 - 氧代类固醇明显少于其他组患者。
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本文引用的文献
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Selection of breast-cancer patients for adrenalectomy or hypophysectomy by determination of urinary 17-hydroxycorticosteroids and aetiocholanolone.
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The discriminant function in early carcinoma of the breast.早期乳腺癌中的判别函数。
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