对乙酰水杨酸的过敏反应。I. 使用通过羧基连接到蛋白质上的乙酰水杨酸检测人血清中的抗体。
Hypersensitivity reactions to acetylsalicylic acid. I. Detection of antibodies in human sera using acetylsalicylic acid attached to proteins through the carboxyl group.
作者信息
Amos H E, Wilson D V, Taussig M J, Carlton S J
出版信息
Clin Exp Immunol. 1971 Apr;8(4):563-72.
Abstract
Aspirin–protein conjugates (aspirin coupled to rabbit anti-human `O' antibody and to anti-bacteriophage-Fab') were prepared by a method which links aspirin through its carboxyl group. The protein conjugates were used to raise specific aspirin antibodies in guinea-pigs. Such antibodies helped to characterize the other preparations which were subsequently used to test suspected hypersensitive sera for aspirin antibodies. Although an antibody of aspirin specificity was detected it could not be related to the clinical hypersensitivity state.
摘要
阿司匹林 - 蛋白质偶联物（阿司匹林与兔抗人`O'抗体及抗噬菌体 - Fab'偶联）通过一种将阿司匹林通过其羧基连接的方法制备而成。这些蛋白质偶联物用于在豚鼠体内产生特异性的阿司匹林抗体。此类抗体有助于鉴定后续用于检测疑似过敏血清中阿司匹林抗体的其他制剂。尽管检测到了具有阿司匹林特异性的抗体，但它与临床过敏状态并无关联。
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J Lab Clin Med. 1950 Sep;36(3):416-21.
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