Klammer J, Bichler A, Brabec W, Dapunt O
Z Geburtshilfe Perinatol. 1979 Feb;183(1):12-8.
In 11 cases both twins were of normal weight. In 7 cases one twin and in 12 cases both twins were underweighed (the growth retardation was classified according to the intrauterine growth curves after Hohenauer applicable to our area). The determination of total 24 hours urinary estrogens and serial ultrasonic measurements of biparietal diameters appeared in our study to be the best parameters for the detection of intrauterine growth retardation. Serum HPL determination was unreliable. In addition 2 types of growth retardation in twins could be recognized from the estrogen values. In one, a dysfunction of the fetoplacental unit existed; in the other, the etiology of the growth retardation could not be determined by the methods used in the study (genetic origin?).
11例中,双胞胎体重均正常。7例中一个双胞胎及12例中两个双胞胎体重均低于正常(根据适用于我们地区的霍赫瑙尔子宫内生长曲线对生长迟缓进行分类)。在我们的研究中,24小时尿雌激素总量的测定和双顶径的系列超声测量似乎是检测子宫内生长迟缓的最佳参数。血清人胎盘催乳素测定不可靠。此外,从雌激素值可识别出双胞胎的两种生长迟缓类型。一种是胎儿胎盘单位功能障碍;另一种生长迟缓的病因无法通过该研究中使用的方法确定(遗传起源?)