Matzen K A, Werner K C
Z Orthop Ihre Grenzgeb. 1979 Feb;117(1):21-30.
This study aims at investigating in a group of thirty-five patients whether osteogenesis imperfecta tarda presents a uniform disease pattern in respect of clinical and roentgenological criteria, or whether it can be subdivided into clinical groups. Depending on the severity of the disease, it was possible to subdivide this into two groups: a severe form of osteogenesis imperfecta tarda, and a bland form. This subdivision was effected according to the most conspicuous symptom of frequency of the fracture. The other symptoms do not allow any subdivision into groups since their occurrence is independent of the severity of the disease pattern.
本研究旨在调查一组35名患者,迟发性成骨不全在临床和放射学标准方面是否呈现统一的疾病模式,或者是否可以细分为不同的临床组。根据疾病的严重程度,可将其分为两组:严重型迟发性成骨不全和轻型。这种细分是根据骨折频率这一最明显的症状进行的。其他症状无法进行分组,因为它们的出现与疾病模式的严重程度无关。