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小鼠下丘脑弓状核中多巴胺神经元的拓扑结构。

Topography of the dopamine neurons in the arcuate nucleus of the mouse hypothalamus.

作者信息

Nishizuka M

出版信息

Acta Anat (Basel). 1979;103(1):34-8. doi: 10.1159/000144995.

DOI:10.1159/000144995
PMID:425822
Abstract

The distribution of the dopamine (DA) cell bodies was elucidated within the mouse arcuate nucleus by fluorescence histochemistry. The arcuate nucleus was divided into five regions; heterogeneity in distribution and different amounts of DA among the regional areas were demonstrated. The DA cell bodies containing a large amount of DA, observable even in the arcuate nucleus of the intact mice, distributed in the medial areas of the anterio-central and the middle-central regions and in the dorsal area of the posterior-central region. On the other hand, those containing probably as small amount of DA distributed in the medial area of the rostral region and in the ventral areas of the anterior-central and middle-central regions. They were not observed in the intact mice, but found in the mice treated with nialamide plus alpha-methyldopa. No DA cells were found in the caudal region.

摘要

通过荧光组织化学法阐明了小鼠弓状核内多巴胺(DA)细胞体的分布情况。将弓状核分为五个区域;结果表明区域间存在分布不均和不同数量的DA。含有大量DA的DA细胞体,即使在完整小鼠的弓状核中也可观察到,分布于前中央区和中中央区的内侧区域以及后中央区的背侧区域。另一方面,含有可能少量DA的细胞体分布于吻侧区的内侧区域以及前中央区和中中央区的腹侧区域。在完整小鼠中未观察到这些细胞体,但在接受尼亚酰胺加α-甲基多巴治疗的小鼠中发现了它们。在尾侧区域未发现DA细胞。

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1
Topography of the dopamine neurons in the arcuate nucleus of the mouse hypothalamus.小鼠下丘脑弓状核中多巴胺神经元的拓扑结构。
Acta Anat (Basel). 1979;103(1):34-8. doi: 10.1159/000144995.
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引用本文的文献

1
Cytometric investigations in histochemically identified neurons--changes of fluorescence intensities and nuclear diameters in dopamine neurons of the arcuate nucleus in the cycling rat.组织化学鉴定神经元的细胞计量学研究——发情周期大鼠弓状核多巴胺能神经元荧光强度和核直径的变化
Exp Brain Res. 1980 Feb;38(3):293-8. doi: 10.1007/BF00236648.
2
Testosterone-induced alterations in the reactivity pattern of the neurons in the arcuate nucleus of male mice. A karyometric study.睾酮诱导雄性小鼠弓状核神经元反应模式的改变。一项细胞核测量研究。
Cell Tissue Res. 1983;229(1):183-9. doi: 10.1007/BF00217890.