[糖皮质激素治疗后奶牛血液和子宫内膜分泌物中的电解质]
[Electrolytes of the blood and endometrial secretions of the cow following glucocorticoid therapy].
作者信息
Ibrahim M, Guay P, Lamothe P
出版信息
Can J Comp Med. 1972 Apr;36(2):160-6.
The effect of two synthetic glucocorticoids, 9-fluoroprednisolone acetate and dexamethasone (9-fluoro, 16-methylprednisolone) was studied on 12 normally breeding cows. Na, Mg, K, Ca and P concentrations were evaluated in the serum and in the uterine fluid at four stages of the estrous cycle. No significant changes were noted in Na and Ca concentration in either serum or uterine fluid. On the other hand, significant changes in the Mg, K and P were observed. Both drugs have caused a decrease in the content of Mg in the serum (P<0.05) during diestrus, a fall in the level of uterine K (P<0.01) during proestrus and a decrease of P during proestrus both in serum (P<0.001 after dexamethasone treatment) and in uterine fluid (P<0.001 for both drugs). It is obvious that the two drugs change the chemical composition of blood and endometrial secretions. This could jeopardize the survival of the spermatozoids and of the ovum as well as the fertilization and the implantation processes.
研究了两种合成糖皮质激素，即醋酸9-氟泼尼松龙和地塞米松（9-氟，16-甲基泼尼松龙）对12头正常繁殖奶牛的影响。在发情周期的四个阶段评估了血清和子宫液中的钠、镁、钾、钙和磷浓度。血清或子宫液中的钠和钙浓度均未发现显著变化。另一方面，观察到镁、钾和磷有显著变化。两种药物均导致在发情后期血清中的镁含量降低（P<0.05），在发情前期子宫钾水平下降（P<0.01），并且在发情前期血清（地塞米松治疗后P<0.001）和子宫液（两种药物均为P<0.001）中的磷含量均降低。显然，这两种药物改变了血液和子宫内膜分泌物的化学成分。这可能会危及精子和卵子的存活以及受精和着床过程。
Zotero 插件