在野生型粗糙脉孢菌中直接诱导对奎尼酸和莽草酸分解代谢组成型的突变体（qa-1c）。
Direct induction in wild-type Neurospora crassa of mutants (qa-1 c ) constitutive for the catabolism of quinate and shikimate.
作者信息
Partridge C W, Case M E, Giles N H
出版信息
Genetics. 1972 Nov;72(3):411-7. doi: 10.1093/genetics/72.3.411.
Abstract
A color test has been developed for the selection and identification of mutants in Neurospora crassa, constitutive for the three normally inducible enzymes which convert quinate to protocatechuate. By this means seven such mutants have been recovered after ultra violet irradiation of wild type and have been shown to be allelic (or very closely linked) to the qa-1(C) mutants previously obtained by other means. Thus, the regulation of the synthesis of these three catabolic enzymes is indicated to be under the control of a single gene, qa-1(+).
摘要
已开发出一种颜色测试方法，用于筛选和鉴定粗糙脉孢菌中的突变体，这些突变体对于将奎尼酸转化为原儿茶酸的三种通常可诱导的酶具有组成型表达。通过这种方法，在对野生型进行紫外线照射后，已获得了七个这样的突变体，并已证明它们与先前通过其他方法获得的qa-1(C)突变体等位（或紧密连锁）。因此，表明这三种分解代谢酶的合成调控受单个基因qa-1(+)的控制。
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Direct induction in wild-type Neurospora crassa of mutants (qa-1 c ) constitutive for the catabolism of quinate and shikimate.在野生型粗糙脉孢菌中直接诱导对奎尼酸和莽草酸分解代谢组成型的突变体（qa-1c）。
Genetics. 1972 Nov;72(3):411-7. doi: 10.1093/genetics/72.3.411.
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Genetic evidence on the organization and action of the qa-1 gene product: a protein regulating the induction of three enzymes in quinate catabolism in Neurospora crassa.关于qa-1基因产物的组织与作用的遗传学证据：一种调节粗糙脉孢菌中奎尼酸分解代谢过程中三种酶诱导作用的蛋白质。
Proc Natl Acad Sci U S A. 1975 Feb;72(2):553-7. doi: 10.1073/pnas.72.2.553.
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Studies on the mechanism of reversion in biochemical mutants of Neurospora crassa.粗糙脉孢菌生化突变体回复突变机制的研究。
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A method for isolating constitutive mutants for carbohydrate-catabolizing enzymes.一种分离碳水化合物分解酶组成型突变体的方法。
Biochim Biophys Acta. 1962 Jul 2;60:422-4. doi: 10.1016/0006-3002(62)90423-7.
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[The cytochemical determination of dehydrogenases in fungi. I. Investigation and prospects for the methodology].[真菌中脱氢酶的细胞化学测定。I. 方法学研究与展望]
Arch Mikrobiol. 1967 Jul 6;57(4):285-306.
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Constitutive mutants in a regulatory gene exerting positive control of quinic acid catabolism in Neurospora crassa.在粗糙脉孢菌中，对奎尼酸分解代谢发挥正调控作用的调控基因中的组成型突变体。
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1555-9. doi: 10.1073/pnas.68.7.1555.
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