Medvetskiĭ E B, Shalimov S A, Kadoshchuk T A
Arkh Patol. 1979;41(2):41-5.
Biopsies of pancreatic tissue in 54 patients with chronic pancreatitis were studied histologically and electron microscopically. Pathomorphological criteria of this disease include: dyscomplexation of acini, necroses, hemorrhages, inflammatory reaction, pseudocystosis, lipomatosis, condensation of secretory masses, and formation of concrements, hyperplasia, metaplasia, and increased desquamation of ductular epithelium, hyperplasia of Langerhans islands, damage of the vessels and perineural spaces, fibrosis. The increased permeability of ductal epithelium, increased synthesis of protein substances, formation of concrements and specific antibody are conducive to exacerbation of chronic pancreatitis.
对54例慢性胰腺炎患者的胰腺组织活检进行了组织学和电子显微镜研究。该疾病的病理形态学标准包括：腺泡结构紊乱、坏死、出血、炎症反应、假性囊肿形成、脂肪沉积、分泌物质浓缩、结石形成、增生、化生、导管上皮脱屑增加、朗格汉斯岛增生、血管和神经周围间隙损伤、纤维化。导管上皮通透性增加、蛋白质物质合成增加、结石形成和特异性抗体有利于慢性胰腺炎的加重。
