Butov Iu L
Arkh Patol. 1979;41(3):71-6.
The paper analyses interrelationships between chronic gastritis and carcinoma of the stomach. It has been recognized that various forms of chronic gastritis preceed carcinoma of the stomach. The source of the carcinoma origin is the epithelium of the gastric pit, intestinal and mixed epithelium. The nearest precursors of the carcinoma are foci of dysplasia of the epithelium developing in pits, intestinal cryptae and mixed glands. Proceeding from the regular emergence of the stomach carcinoma against the background of chromic gastritis, features of carcinogenesis in the stomach, and morphogenesis of chronic gastritis, the authors substantiate the pathogenetic connection between chronic gastritis and carcinoma of the stomach. Secondary changes in the gastric system have been found to develop in the III--IV stages of carcinoma. The main morphological features of carcinoma of the stomach of different histogenesis are characterized.
本文分析了慢性胃炎与胃癌之间的相互关系。人们已经认识到，各种形式的慢性胃炎先于胃癌出现。癌的起源部位是胃小凹上皮、肠上皮及混合上皮。癌的最直接前体是在胃小凹、肠腺隐窝及混合腺中发生的上皮发育异常灶。基于慢性胃炎背景下胃癌的规律性发生、胃内致癌作用的特点以及慢性胃炎的形态发生过程，作者证实了慢性胃炎与胃癌之间的发病学联系。已发现胃部系统的继发性改变在癌的Ⅲ - Ⅳ期出现。对不同组织发生类型的胃癌的主要形态学特征进行了描述。
