系统性红斑狼疮及其他结缔组织病中的核糖核酸（RNA）皮肤试验

The ribonucleic acid (RNA) skin test in systemic lupus erythematosus and other connective tissue diseases.

作者信息

Johansson E A, Niemi K M, Halme H

出版信息

Br J Dermatol. 1979 Feb;100(2):127-30. doi: 10.1111/j.1365-2133.1979.tb05549.x.

DOI:10.1111/j.1365-2133.1979.tb05549.x

Abstract

A series of 65 patients with different autoimmune diseases was examined using different RNA-solutions for intradermal skin tests. Clinically positive results were obtained most often in patients with mixed connective tissue disease but quite often also in patients with systemic lupus erythematosus and progressive systemic sclerosis or with some symptoms of an automimmune nature. The histological examination of the biopsies from the test sites revealed that there was no correlation between the clinically positive tests and the histological criteria usually used as a sign of a positive test.

摘要

使用不同的RNA溶液对65例患有不同自身免疫性疾病的患者进行皮内皮肤试验检查。临床上，混合性结缔组织病患者最常出现阳性结果，但系统性红斑狼疮、进行性系统性硬化症患者或有某些自身免疫性质症状的患者也经常出现阳性结果。对试验部位活检组织的组织学检查显示，临床阳性试验与通常用作阳性试验标志的组织学标准之间没有相关性。