大麻吸食者细胞介导免疫的抑制
Inhibition of cellular mediated immunity in marihuana smokers.
作者信息
Nahas G G, Suciu-Foca N, Armand J P, Morishima A
出版信息
Science. 1974 Feb 1;183(4123):419-20. doi: 10.1126/science.183.4123.419.
PMID:4271816
Abstract
The cellular mediated immunity of 51 young chronic marihuana smokers. as evaluated by the lyomphocyte response in vitro to allogeneic cells and to phytohemagglutinin, was significantly decreased and similar to that of patients in whom impairment of T (thymus derived) cell immunity is known to occur. This inhibition of blastogenesis might be related to an impairment of DNA synthesis.
摘要
51名年轻慢性大麻吸食者的细胞介导免疫，通过体外淋巴细胞对同种异体细胞和植物血凝素的反应来评估，显著降低，且与已知发生T（胸腺衍生）细胞免疫损伤的患者相似。这种对细胞增殖的抑制可能与DNA合成受损有关。
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