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Can Med Assoc J. 1979 Feb 3;120(3):305-9.
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An Esp Pediatr. 1981 May;14(5):311-20.
4
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[Tuberculous meningitis in children. (70 cases)].儿童结核性脑膜炎。(70例)
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6
Predictors of mortality in childhood neurotuberculosis: a retrospective study of 84 cases.儿童神经型结核病死亡率的预测因素:84例回顾性研究
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7
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8
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9
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Am J Trop Med Hyg. 2022 Oct 10;107(6):1288-1294. doi: 10.4269/ajtmh.22-0253. Print 2022 Dec 14.
2
Tuberculous Meningitis in Children and Adults: New Insights for an Ancient Foe.儿童和成人结核性脑膜炎:对古老敌人的新见解
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3
Clinical presentations, diagnosis, mortality and prognostic markers of tuberculous meningitis in Vietnamese children: a prospective descriptive study.越南儿童结核性脑膜炎的临床表现、诊断、死亡率及预后标志物:一项前瞻性描述性研究。
BMC Infect Dis. 2016 Oct 18;16(1):573. doi: 10.1186/s12879-016-1923-2.
4
A review of tuberculous meningitis in a Canadian pediatric hospital.加拿大一家儿科医院的结核性脑膜炎综述。
Can J Infect Dis. 1991 Winter;2(4):155-60. doi: 10.1155/1991/638031.
5
Tuberculous meningitis in HIV-infected individuals.HIV感染个体中的结核性脑膜炎。
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Tuberculous meningitis: role of CT in management and prognosis.结核性脑膜炎:CT在管理与预后中的作用
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7
Tuberculosis in a children's hospital.
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本文引用的文献

1
[Study of 216 cases of tuberculous meningitis in children].[216例儿童结核性脑膜炎的研究]
Ann Pediatr (Paris). 1976 May 2;23(5):379-83.
2
Tuberculosis in B.C.G. vaccinated children in Singapore.新加坡接种卡介苗儿童中的结核病
Arch Dis Child. 1961 Oct;36(189):530-6. doi: 10.1136/adc.36.189.530.
3
Long-term follow-up of 100 children who recovered from tuberculous meningitis.对100名结核性脑膜炎康复儿童的长期随访。
Pediatrics. 1961 Nov;28:778-91.
4
THE CHANGING INCIDENCE AND PROGNOSIS OF TUBERCULOUS MENINGITIS.
Am J Med Sci. 1965 Jul;250:46-59. doi: 10.1097/00000441-196507000-00008.
5
THE SEQUELAE OF TUBERCULOUS MENINGITIS.结核性脑膜炎的后遗症
Arch Dis Child. 1964 Jun;39(205):213-25. doi: 10.1136/adc.39.205.213.
6
The present status of the treatment of tuberculosis of the central nervous system.中枢神经系统结核病的治疗现状
Ann N Y Acad Sci. 1963 Feb 28;106:106-23. doi: 10.1111/j.1749-6632.1963.tb16629.x.
7
Tuberculous meningitis in children. A review of 167 untreated and 74 treated patients with special reference to early diagnosis.儿童结核性脑膜炎。对167例未经治疗和74例接受治疗的患者进行回顾,特别提及早期诊断。
J Pediatr. 1960 Dec;57:807-23. doi: 10.1016/s0022-3476(60)80132-1.
8
Results of specific treatment of miliary tuberculosis in children; a follow-up study of 63 patients treated with antimicrobial agents.儿童粟粒性肺结核的特异性治疗结果;63例接受抗菌药物治疗患者的随访研究
N Engl J Med. 1959 Jul 16;261(3):113-20. doi: 10.1056/NEJM195907162610302.
9
Corticosteroids as an adjuvant to the chemotherapy of tuberculous meningitis.
Tubercle. 1966 Mar;47(1):75-91. doi: 10.1016/s0041-3879(66)80052-1.
10
Prognosis in tuberculous meningitis.结核性脑膜炎的预后
Indian Pediatr. 1970 May;7(5):257-61.

儿童结核性脑膜炎:79例患者的回顾性研究及预后因素分析

Tuberculous meningitis in children: a retrospective study of 79 patients, with an analysis of prognostic factors.

作者信息

Delage G, Dusseault M

出版信息

Can Med Assoc J. 1979 Feb 3;120(3):305-9.

PMID:427668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1819003/
Abstract

A study of 79 cases of tuberculous meningitis in children, with an emphasis on prognostic factors, was conducted by means of a review of hospital records and completion of a follow-up questionnaire. The survival rate was 62%. Stage 3 disease (with severe changes in the sensorium and often severe neurologic abnormalities) at the time of admission, age 3 years or less, associated miliary tuberculosis and delay in the initiation of therapy correlated significantly with poor outcome. Severe neurologic complications in the acute phase were also related to poor outcome and severe sequelae. General recommendations pertaining to treatment are made.

摘要

通过回顾医院记录并完成一份随访问卷,对79例儿童结核性脑膜炎病例进行了研究,重点关注预后因素。存活率为62%。入院时处于3期疾病(意识严重改变且常伴有严重神经异常)、3岁及以下、合并粟粒性结核以及治疗开始延迟与不良预后显著相关。急性期严重的神经并发症也与不良预后和严重后遗症有关。文中给出了有关治疗的一般性建议。