儿童结核性脑膜炎：79例患者的回顾性研究及预后因素分析
Tuberculous meningitis in children: a retrospective study of 79 patients, with an analysis of prognostic factors.
作者信息
Delage G, Dusseault M
出版信息
Can Med Assoc J. 1979 Feb 3;120(3):305-9.
Abstract
A study of 79 cases of tuberculous meningitis in children, with an emphasis on prognostic factors, was conducted by means of a review of hospital records and completion of a follow-up questionnaire. The survival rate was 62%. Stage 3 disease (with severe changes in the sensorium and often severe neurologic abnormalities) at the time of admission, age 3 years or less, associated miliary tuberculosis and delay in the initiation of therapy correlated significantly with poor outcome. Severe neurologic complications in the acute phase were also related to poor outcome and severe sequelae. General recommendations pertaining to treatment are made.
摘要
通过回顾医院记录并完成一份随访问卷，对79例儿童结核性脑膜炎病例进行了研究，重点关注预后因素。存活率为62%。入院时处于3期疾病（意识严重改变且常伴有严重神经异常）、3岁及以下、合并粟粒性结核以及治疗开始延迟与不良预后显著相关。急性期严重的神经并发症也与不良预后和严重后遗症有关。文中给出了有关治疗的一般性建议。
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