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Comparison of cytotoxic effect and cellular uptake of 1-beta-D-arabinofuranosylcytosine and its N4-acyl derivatives, using cultured KB cells.

作者信息

Tsuruo T, Iida H, Tsukagoshi S, Sakurai Y

出版信息

Cancer Res. 1979 Mar;39(3):1063-70.

PMID:427747
Abstract
摘要

相似文献

1
Comparison of cytotoxic effect and cellular uptake of 1-beta-D-arabinofuranosylcytosine and its N4-acyl derivatives, using cultured KB cells.使用培养的KB细胞比较1-β-D-阿拉伯呋喃糖基胞嘧啶及其N4-酰基衍生物的细胞毒性作用和细胞摄取。
Cancer Res. 1979 Mar;39(3):1063-70.
2
Membrane affinity and metabolism of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine into cultured KB cells.N4-棕榈酰基-1-β-D-阿拉伯呋喃糖基胞嘧啶在培养的KB细胞中的膜亲和力和代谢
Cancer Res. 1981 Nov;41(11 Pt 1):4484-8.
3
Enzyme catalyzation of the deacylation of N4-acyl derivatives of 1-beta-D-arabinofuranosylcytosine in the mouse liver microsome.1-β-D-阿拉伯呋喃糖基胞嘧啶的N4-酰基衍生物在小鼠肝脏微粒体中的脱酰基酶催化作用。
Cancer Res. 1982 Jun;42(6):2250-4.
4
Purification and characterization of an amidohydrolase for N4-long-chain fatty acyl derivatives of 1-beta-D-arabinofuranosylcytosine from mouse liver microsomes.从小鼠肝脏微粒体中纯化并鉴定一种针对1-β-D-阿拉伯呋喃糖基胞嘧啶N4-长链脂肪酰基衍生物的酰胺水解酶。
Cancer Res. 1984 Mar;44(3):1187-93.
5
Production of N4-succinyl-1-beta-D-arabinofuranosylcytosine, a novel metabolite of N4-behenoyl-1-beta-D-arabinofuranosylcytosine, in mice and its biological significance.N4-山嵛酰基-1-β-D-阿拉伯呋喃糖基胞嘧啶的新型代谢产物N4-琥珀酰基-1-β-D-阿拉伯呋喃糖基胞嘧啶在小鼠体内的产生及其生物学意义。
Cancer Res. 1981 Jun;41(6):2501-6.
6
Antitumor activities of newly synthesized N4-acyl-1-beta-D-arabinofuranosylcytosine.新合成的N4-酰基-1-β-D-阿拉伯呋喃糖基胞嘧啶的抗肿瘤活性
Cancer Res. 1976 Aug;36(8):2726-32.
7
Low density lipoprotein and liposome mediated uptake and cytotoxic effect of N4-octadecyl-1-beta-D-arabinofuranosylcytosine in Daudi lymphoma cells.低密度脂蛋白和脂质体介导的N4-十八烷基-1-β-D-阿拉伯呋喃糖基胞嘧啶在Daudi淋巴瘤细胞中的摄取及细胞毒性作用。
Br J Cancer. 1999 Jul;80(10):1542-9. doi: 10.1038/sj.bjc.6690558.
8
Cytotoxicity of N4-behenoyl-1-beta-D-arabinofuranosylcytosine through gradual conversion to 1-beta-D-arabinofuranosylcytosine in HeLa cells.N4-山嵛酰基-1-β-D-阿拉伯呋喃糖基胞嘧啶在HeLa细胞中通过逐步转化为1-β-D-阿拉伯呋喃糖基胞嘧啶的细胞毒性。
Anticancer Res. 1989 Jan-Feb;9(1):41-4.
9
Synthesis and structure-activity studies in vivo of liposomal phospholipid-N4-palmitoyl- and N4-hexadecyl-1-beta-D-arabinofuranosylcytosine conjugates.脂质体磷脂 - N4 - 棕榈酰基和N4 - 十六烷基 - 1 - β - D - 阿拉伯呋喃糖基胞嘧啶缀合物的体内合成及构效关系研究
Anticancer Drug Des. 1996 Sep;11(6):451-62.
10
Effects of N4-behenoyl-1-beta-D-arabinofuranosylcytosine on blast progenitors of acute myeloblastic leukemia.
Cancer Res. 1990 Dec 1;50(23):7587-92.

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Intracellular activation and cytotoxic action of RS-1541 against cultured human tumor cells.
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2
Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil.1-己基氨基甲酰基-5-氟尿嘧啶对小鼠结肠腺癌和Lewis肺癌的抑制作用
Cancer Chemother Pharmacol. 1980;4(2):83-7. doi: 10.1007/BF00254027.
3
Phase I clinical and pharmacokinetic study of orally administered N4-palmitoyl-1-beta-D-arabinofuranosylcytosine.口服N4-棕榈酰-1-β-D-阿拉伯呋喃糖基胞嘧啶的I期临床及药代动力学研究
Med Oncol Tumor Pharmacother. 1987;4(2):67-73.
4
Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo.
Cancer Chemother Pharmacol. 1988;21(1):71-4. doi: 10.1007/BF00262744.
5
A benzophenazine derivative, N-beta-dimethylaminoethyl 9-carboxy-5-hydroxy-10-methoxy-benzo[a]phenazine-6-carboxamide, as a new antitumor agent against multidrug-resistant and sensitive tumors.一种二苯并吩嗪衍生物，N-β-二甲基氨基乙基9-羧基-5-羟基-10-甲氧基-苯并[a]吩嗪-6-甲酰胺，作为一种针对多药耐药性肿瘤和敏感肿瘤的新型抗肿瘤药物。
Cancer Chemother Pharmacol. 1990;26(2):83-7. doi: 10.1007/BF02897249.
6
Biological effects of tolytoxin (6-hydroxy-7-O-methyl-scytophycin b), a potent bioactive metabolite from cyanobacteria.岩藻毒素（6-羟基-7-O-甲基-鞘丝藻素b）的生物学效应，一种来自蓝藻的强效生物活性代谢产物。
Arch Microbiol. 1992;157(5):406-10. doi: 10.1007/BF00249096.