Wyn-Jones G
Equine Vet J. 1979 Jan;11(1):3-10. doi: 10.1111/j.2042-3306.1979.tb01283.x.
The literature is briefly reviewed concerning the clinical features of equine cutaneous tumours. The data from 19 horses with periocular skin tumours are reported together with the results of their treatment by implantation with radioactive gold198. The principles governing the implantation of radioactive sources are explained and a method for computing the initial activity of the sources is outlined. Five histologically different tumour types were treated in this series of 19 horses, 2 horses were bilaterally affected. The techniques of implantation using a simple needle/stillette combination and a purpose built gold grain implantation gun are described and the postoperative course of the animals is traced. The treatment was successful in ablating the tumour mass and preventing regrowth in 19 of 21 periocular tumour groups. The cosmetic effects of the treatment were found to be satisfactory. Emphasis is laid on the care needed in handling the radioactive material and on the need for a thorough understanding of the principles involved in radiotherapy. Doses received by the operator during an implantation procedure are quoted which show that the technique is safe as well as being effective.
本文简要回顾了有关马皮肤肿瘤临床特征的文献。报告了19匹患有眼周皮肤肿瘤的马的数据，以及通过植入放射性金198进行治疗的结果。解释了放射性源植入的原则，并概述了计算源初始活度的方法。在这19匹马的系列病例中，治疗了5种组织学不同的肿瘤类型，2匹马双侧患病。描述了使用简单针/探针组合和特制金粒植入枪的植入技术，并追踪了动物的术后病程。在21个眼周肿瘤组中的19组中，该治疗成功消融了肿瘤块并防止了肿瘤复发。发现该治疗的美容效果令人满意。强调了处理放射性物质时所需的注意事项以及对放射治疗所涉及原理有透彻理解的必要性。引用了操作人员在植入过程中所接受的剂量，表明该技术既安全又有效。
