Easton J M, Hiatt C W
Science. 1966 Feb 4;151(3710):582-3. doi: 10.1126/science.151.3710.582.
Twelve consecuttive passages of simian virus 40, made in the presence of adenovirus 4 and antiserum to simian virus 40, indicated that simian virus 40 would multiply almost indefinitely under these conditions. The adenovirus and the simian virus had previously replicated together in the absence of antiserum. These data support the conclusion that the SV-40 genome is incorporated within the protein coats of adenovirus 4.
在腺病毒4和抗猴病毒40血清存在的情况下,对猴病毒40进行了连续十二代传代,结果表明猴病毒40在这些条件下几乎可以无限增殖。腺病毒和猴病毒此前曾在无抗血清的情况下共同复制。这些数据支持了SV - 40基因组被整合到腺病毒4的蛋白衣壳内的结论。