Dressler F
Fortschr Med. 1979 Apr 5;97(13):627-31.
Lonarid N was used in 78 children suffering from different febrile diseases. It was available in suppositories for infants and children. Body temperature dropped to subfebrile values in 78.5% of all doses. In 8.6% a lowering effect was distinct but incomplete, in 12.9% no satisfying effect occurred. After one hour average lowering of 1.5 to 1.9 degrees C was seen in nearly half of the cases, after three hours normal temperatures were found in all cases responding to Lonarid N at all. Lonarid N is acting promptly and normal body temperature is reached as expected. No complications of therapy were seen.
78名患有不同发热性疾病的儿童使用了洛那立得N。有适合婴幼儿和儿童使用的栓剂剂型。所有剂量中,78.5%的患儿体温降至低热值。8.6%的患儿降温效果明显但不完全,12.9%的患儿未出现满意效果。近半数病例在1小时后平均降温1.5至1.9摄氏度,3小时后,所有对洛那立得N有反应的病例体温均恢复正常。洛那立得N起效迅速,能如期使体温恢复正常。未观察到治疗并发症。