印度蓝环蛇毒液与从中分离出一种假定胆碱能离子载体标记物的毒液的比较。
Comparison of Bungarus caeruleus venom with the venom from which a putative cholinergic ionophore marker was isolated.
作者信息
Noble R L, Cooper M J, Hess G P
出版信息
Int J Pept Protein Res. 1979 Feb;13(2):142-5. doi: 10.1111/j.1399-3011.1979.tb01862.x.
Comparisons are described between Bungarus caeruleus venom and the actual venom from which a putative marker for the cholinergic ionophore, called ceruleotoxin, was isolated. The venoms are shown to be different by two procedures for ion exchange chromatography and by isoelectric focusing on polyacrylamide gel. The activities of the purified "ceruleotoxin" as an inhibitor of acetylcholine receptor-mediated ion flux and as a phospholipase have been reported (Bon & Changeux, 1977b). The results reported herein suggest that this toxin is from an unknown origin.
本文描述了印度环蛇毒液与实际毒液之间的比较，从实际毒液中分离出了一种假定的胆碱能离子载体标记物，即蓝环蛇毒素。通过两种离子交换色谱法和聚丙烯酰胺凝胶等电聚焦法显示，这两种毒液是不同的。纯化后的“蓝环蛇毒素”作为乙酰胆碱受体介导的离子通量抑制剂和磷脂酶的活性已有报道（邦和尚热，1977b）。本文报道的结果表明，这种毒素来源不明。
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