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β-肾上腺素能阻滞剂对中脑网状结构生物电活动的影响

[Effect of beta-adrenergic blockaders on the bioelectrical activity of the mesenchephalic reticular formation].

作者信息

Ovcharov R, Iosifov T, Radev R

出版信息

Eksp Med Morfol. 1975;14(3):121-8.

PMID:4291
Abstract

The authors examined the beta-adrenergic structures in the mesencephalic formation (MSF) in view of establishing their role on the activity of MSF in view of establishing the in rols on the activity of MSF itself and the relationship of the same formation with the cerebral cortex and the lymbic system. It was established that beta-adrenergic blockers after their local application in MSF could inhibit its function. The data from the effect on the induced bioelectrical activity indicated also diminution in the functional activity of MSF. The authors found that the inhibiting influences of beta-blockers were abolished by their antagonist isoprenalite. An inference is made that there are beta-adrenergic structures, which act excitatory.

摘要

作者研究了中脑结构(MSF)中的β-肾上腺素能结构,旨在确定其对MSF活动的作用,以及该结构本身的活动情况,及其与大脑皮层和边缘系统的关系。研究发现,β-肾上腺素能阻滞剂局部应用于MSF后可抑制其功能。对诱导生物电活动的影响数据也表明MSF的功能活性降低。作者发现,β-阻滞剂的抑制作用可被其拮抗剂异丙肾上腺素消除。由此推断,存在起兴奋作用的β-肾上腺素能结构。

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