实验性移行细胞癌的左旋咪唑免疫疗法
Levamisole immunotherapy of experimental transitional cell carcinoma.
作者信息
Lamm D L, Yee G N, Reichert D F, Radwin H M
出版信息
Invest Urol. 1979 Jan;16(4):286-8.
PMID:429122
Abstract
Levamisole, in doses comparable to those under clinical investigation, was shown to significantly (P less than 0.02) delay the onset of transplanted transitional cell carcinoma of C3H mice. The growth of transplanted tumors was inhibited and animal survival prolonged with Levamisole treatment. Further progress in the immunotherapy of transitional cell carcinoma may be aided by such models.
摘要
左旋咪唑，在与临床研究中所使用剂量相当的情况下，被证明能显著（P小于0.02）延迟C3H小鼠移植性移行细胞癌的发病时间。左旋咪唑治疗可抑制移植肿瘤的生长并延长动物存活时间。此类模型可能有助于移行细胞癌免疫治疗的进一步进展。
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