Macarone-Palmieri R, Chapuis G, Saegesser F, Boumghar M
Helv Chir Acta. 1979 Feb;45(6):703-6.
This study is composed of 7 hyperlipidaemic patients (type II, n = 4; type IV, n = 3), aged 33 to 59 years. These patients underwent a partial ileal by-pass, and the immediate post-operative period was uneventful. Six months post-operatively, serum levels of cholesterol and triglycerides were 45 and 44% of the pre-operative values. Serum electrolytes remained unchanged as well as liver function tests. In the first few days post-operatively, diarrhoea was a frequent complaint; by the 6th post-operative month, the stools numbered 2-3 per day in patients not receiving any medical treatment. Average weight loss was 6 +/- 1.3%. These preliminary results may confirm that partial ileal by-pass produces favourable metabolic changes. However, screening for late complications is to be further investigated, and the effectiveness of the operative procedure must still be evaluated.
本研究由7名高脂血症患者组成（II型，n = 4；IV型，n = 3），年龄在33至59岁之间。这些患者接受了部分回肠旁路手术，术后即刻恢复顺利。术后6个月，血清胆固醇和甘油三酯水平分别为术前值的45%和44%。血清电解质以及肝功能检查均保持不变。术后头几天，腹泻是常见的主诉；到术后第6个月，未接受任何药物治疗的患者每天排便2 - 3次。平均体重减轻6 +/- 1.3%。这些初步结果可能证实部分回肠旁路手术可产生有利的代谢变化。然而，晚期并发症的筛查有待进一步研究，手术操作的有效性仍需评估。
