Eisenhoffer N, Rouge J C, Faidutti B, Friedli B
Helv Paediatr Acta. 1979 Feb;34(1):85-91.
The case is reported of a newborn with pulmonary valvular subatresia and intact interventricular septum and moderate right ventricular hypoplasia, treated with pulmonary commissurotomy alone. In the immediate postoperative period the ductus arteriosus closed, resulting in deep hypoxia and acidosis. With the infusion of PG E2 the ductus reopened and the baby's condition improved markedly. The ductus was kept open for 20 days, during which time adaptation of the right ventricle must have occurred. Indeed, after definitive spontaneous closure of the ductus, right ventricular output proved sufficient to insure satisfactory pulmonary perfusion.
报道了一例患有肺动脉瓣下闭锁、室间隔完整且右心室中度发育不全的新生儿，仅接受了肺动脉瓣切开术治疗。术后即刻，动脉导管关闭，导致严重缺氧和酸中毒。输注前列腺素E2后，动脉导管重新开放，患儿病情明显改善。动脉导管开放了20天，在此期间右心室必定发生了适应性变化。事实上，在动脉导管最终自然关闭后，右心室输出量证明足以确保满意的肺灌注。
