Moore T M, Meyers M H, Patzakis M J, Terry R, Harvey J P
J Bone Joint Surg Am. 1979 Apr;61(3):375-80.
Five hundred and thirty-one closed biopsies have been done in our general hospital since 1967. Four hundred and eighty-four were for lesions of bone and forty-seven were for soft-tissue lesions. More than half of the lesions were infections or nonspecifically reactive. The procedure was done under local anesthesia in 73 per cent and roentgenographic or image-intensifier control was generally required. The Craig needle was used for cancellous bone near vital structures; the Michele trephine, for cortical or sclerotic bone at a distance from vital structures; and a special needle was used for soft tissue. Closed biopsy provided an adequate specimen that was accurately diagnosed in 66 per cent of bone lesions and in 76 per cent of soft-tissue lesions. This compared favorably with both aspiration and open-biopsy success rates reported by others, and was accompanied by a 1 per cent complication rate, mostly neural and mostly in association with vertebral lesions.
自1967年以来，我院已进行了531例闭合活检。其中484例针对骨病变，47例针对软组织病变。超过半数的病变为感染或非特异性反应性病变。该操作73%在局部麻醉下进行，通常需要X线或影像增强器引导。对于重要结构附近的松质骨，使用克雷格针；对于距重要结构有一定距离的皮质骨或硬化骨，使用米歇尔环锯；对于软组织，则使用特殊的针。闭合活检所获取的标本足够用于诊断，骨病变的诊断准确率为66%，软组织病变为76%。这一结果优于其他报道的穿刺活检和开放活检的成功率，且并发症发生率为1%，主要为神经并发症，大多与椎体病变相关。
