Vivès J F, Richard J L, Barneon G, Schved J F, Janbon C, Vallat G
Sem Hop. 1979;55(37-38):1737-41.
A case is reported of a 49 years-old man who presented with cutaneous and muscular manifestations revealing periarteritis nodosa. Two years after detection of this disease occured a preleukemic condition and four years later a chronic lymphocytic leukaemia is discovered. In clinical course appeared a tuberous infiltration of the face and a sudden bilateral deafness. Regression of these two abnormalities is obtained after administration of prednisolone. The patient died of generalized infectious process postoperatively. From these clinical and pathological findings relations between periarteritis and CLL, occurence of deafness and cutaneous lesions are discussed. The relationship between the development of CLL and the immunosuppressive treatment is considered.
报告了一例49岁男性患者,其皮肤和肌肉表现提示结节性多动脉炎。在发现该疾病两年后出现白血病前期状态,四年后发现慢性淋巴细胞白血病。临床过程中出现面部结节性浸润和突然的双侧耳聋。给予泼尼松龙后,这两种异常情况有所缓解。患者术后死于全身性感染过程。根据这些临床和病理发现,讨论了结节性多动脉炎与慢性淋巴细胞白血病之间的关系、耳聋和皮肤病变的发生情况。还考虑了慢性淋巴细胞白血病的发展与免疫抑制治疗之间的关系。