Maayan M L, Ingbar S H
Science. 1968 Oct 4;162(3849):124-5. doi: 10.1126/science.162.3849.124.
In isolated thyroid cells I-epinephrine (0.1 and 10.0 micrograms per milliliter), norepinephrine and isoproterenol consistently stimulated the accumulation and organic binding of iodine. The effect was partially inhibited by phentolamine, but not propranolol, and hence may be mediated by alpha receptors. Theophylline did not mimic or enhance the epinephrine effect, suggesting that the latter may not result from activation of adenyl cyclase.
在分离的甲状腺细胞中，1-肾上腺素（每毫升0.1和10.0微克）、去甲肾上腺素和异丙肾上腺素持续刺激碘的摄取和有机结合。酚妥拉明可部分抑制该作用，而普萘洛尔则无此作用，因此该作用可能由α受体介导。茶碱不能模拟或增强肾上腺素的作用，提示肾上腺素的作用可能不是由腺苷酸环化酶激活所致。
