Harrison M J, Thomas D J, Du Boulay G H, Marshall J
J Neurol Sci. 1979 Feb;40(2-3):97-103. doi: 10.1016/0022-510x(79)90195-3.
Fifty-two patients presenting with dementia were divided into a group in whom clinical features suggested an ischaemic basis (multi-infarct dementia) and a group in whom a primary degenerative process seemed more likely. Focal EEG changes and angiographic evidence of ischeamic areas and atheromatous disease of intracranial vessels were more common in the "ischaemic" than in the primary degenerative group. CBF was significantly reduced in the former but the regional pattern was equally distorted in the two groups. These findings strengthen the belief that the ischaemic score can identify those patients whose dementia is associated with vascular disease.
52例患有痴呆症的患者被分为两组，一组患者的临床特征提示存在缺血性基础（多发梗死性痴呆），另一组患者似乎更有可能存在原发性退行性病变。与原发性退行性病变组相比，“缺血性”组的局灶性脑电图改变、缺血区域的血管造影证据以及颅内血管动脉粥样硬化疾病更为常见。前者的脑血流量显著降低，但两组的区域模式同样紊乱。这些发现强化了这样一种信念，即缺血评分可以识别那些痴呆症与血管疾病相关的患者。
