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Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.

作者信息

Durham J P, Ives D H

出版信息

Mol Pharmacol. 1969 Jul;5(4):358-75.

PMID:4308509
Abstract
摘要

相似文献

1
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.脱氧胞苷激酶。I. 在正常组织和肿瘤组织中的分布以及脱氧胞苷与1-β-D-阿拉伯呋喃糖基胞嘧啶磷酸化的相互关系。
Mol Pharmacol. 1969 Jul;5(4):358-75.
2
Metabolism of 1-beta-D-arabinofuranosylcytosine in leukemia L1210: studies with intact cells.
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3
Comparative studies of fluorinated pyrimidines with various cell lines.
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4
Biochemical and genetic studies of a mutant strain of mouse leukemia L1210 resistant to 1-beta-D-arabinofuranosylcytosine (Cytarabine).
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5
Metabolism of 1-beta-D-arabinofuranosylcytosine in leukemia L1210: nucleoside and nucleotide kinases in cell-free extracts.
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Influence of tetrahydrouridine on the phosphorylation of 1-beta-D-arabinofuranosyl-cytosine (ara-C) by enzymes from solid tumors in vitro.四氢尿苷对实体瘤来源的酶在体外磷酸化1-β-D-阿拉伯呋喃糖基胞嘧啶（阿糖胞苷）的影响。
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[Ribonuclease of histones in liver and hepatoma].
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Activities of DNA nucleotidyltransferases and other enzymes in cell-free preparations from hepatomas of different growth rates.不同生长速率肝癌细胞无细胞制剂中DNA核苷酸转移酶及其他酶的活性
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Phosphorylation of 5-halogenated deoxycytidine analogues by deoxycytidine kinase.脱氧胞苷激酶对5-卤代脱氧胞苷类似物的磷酸化作用。
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10
Effect of phosphorylated cyclocytidine on deoxyribonucleic acid polymerase.
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Novel PET probes specific for deoxycytidine kinase.新型脱氧胞苷激酶特异性正电子发射断层扫描探针
J Nucl Med. 2010 Jul;51(7):1092-8. doi: 10.2967/jnumed.109.073361. Epub 2010 Jun 16.
2
An Escherichia coli system expressing human deoxyribonucleoside salvage enzymes for evaluation of potential antiproliferative nucleoside analogs.一种表达人脱氧核苷补救酶的大肠杆菌系统，用于评估潜在的抗增殖核苷类似物。
Antimicrob Agents Chemother. 1998 Oct;42(10):2620-5. doi: 10.1128/AAC.42.10.2620.
3
Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment.
2'-取代脱氧胞苷类似物对核糖核苷酸还原酶的抑制作用：在艾滋病治疗中的可能应用。
Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8403-7. doi: 10.1073/pnas.91.18.8403.
4
New targets for pyrimidine antimetabolites for the treatment of solid tumours. 2: Deoxycytidine kinase.用于实体瘤治疗的嘧啶抗代谢物新靶点。2：脱氧胞苷激酶。
Pharm World Sci. 1994 Apr 15;16(2):104-12. doi: 10.1007/BF01880661.
5
Interspecies differences in the kinetic properties of deoxycytidine kinase elucidate the poor utility of a phase I pharmacologically directed dose-escalation concept for 2-chloro-2'-deoxyadenosine.
Cancer Chemother Pharmacol. 1995;36(6):524-9. doi: 10.1007/BF00685803.
6
Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro.1-β-D-阿拉伯呋喃糖基胞嘧啶、胸腺嘧啶核苷和羟基脲在体外对人B细胞和白血病原始细胞的协同相互作用。
Proc Natl Acad Sci U S A. 1981 Aug;78(8):5132-6. doi: 10.1073/pnas.78.8.5132.
7
Isotope-dilution analysis of the effects of deoxyguanosine and deoxyadenosine on the incorporation of thymidine and deoxycytidine by hydroxyurea-treated thymus cells.脱氧鸟苷和脱氧腺苷对羟基脲处理的胸腺细胞掺入胸苷和脱氧胞苷影响的同位素稀释分析。
Biochem J. 1980 Sep 15;190(3):721-30. doi: 10.1042/bj1900721.
8
Cytosine arabinoside triphosphate production in human leukaemic myeloblasts: interactions with deoxycytidine.人白血病成髓细胞中三磷酸阿糖胞苷的产生：与脱氧胞苷的相互作用
Cancer Chemother Pharmacol. 1981;5(3):185-92. doi: 10.1007/BF00258478.
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Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo.脱氧胞苷激酶介导的脱氧腺苷类似物在体外对人恶性淋巴母细胞及在体内对小鼠L1210白血病的毒性作用。
Proc Natl Acad Sci U S A. 1980 Nov;77(11):6865-9. doi: 10.1073/pnas.77.11.6865.
10
Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.腺苷激酶缺陷型人淋巴母细胞系对脱氧腺苷在生长、S-腺苷同型半胱氨酸水解酶失活及dATP积累方面作用的抗性。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4292-6. doi: 10.1073/pnas.77.7.4292.