儿童急性阿米巴痢疾的治疗。甲硝唑与去氢依米丁、四环素和糠酯酰胺联合用药的对比试验。
Treatment of children with acute amoebic dysentery. Comparative trial of metronidazole against a combination of dehydroemetine, tetracycline, and diloxanide furoate.
作者信息
Rubidge C J, Scragg J N, Powell S J
出版信息
Arch Dis Child. 1970 Apr;45(240):196-7. doi: 10.1136/adc.45.240.196.
Metronidazole cured 17 out of 20 children with acute amoebic dysentery. The 3 failures were later treated with dehydroemetine, tetracycline, and diloxanide furoate, but 2 required further courses of amoebicides before they were cured. A combination of dehydroemetine, tetracycline, and diloxanide furoate produced cure in 16 out of 19 children. The 3 failures were subsequently treated with metronidazole. 2 were cured; the remaining patient did not reattend for follow-up. Metronidazole is as effective as the previously favoured combined regimen of amoebicides in children with amoebic dysentry. It is a safe and simple form of treatment.
甲硝唑治愈了20例急性阿米巴痢疾患儿中的17例。3例未治愈的患儿后来接受了去氢依米丁、四环素和糠酯酰胺治疗，但其中2例在治愈前还需要进一步的抗阿米巴疗程。去氢依米丁、四环素和糠酯酰胺联合治疗使19例患儿中的16例治愈。3例未治愈的患儿随后接受了甲硝唑治疗。2例治愈；其余1例患者未再来接受随访。在患阿米巴痢疾的儿童中，甲硝唑与先前常用的联合抗阿米巴疗法效果相当。它是一种安全、简便的治疗方式。
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