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Radiation and the phagocytic function of the reticuloendothelial system. II. Mechanism of RES stimulation after irradiation.辐射与网状内皮系统的吞噬功能。II. 辐射后网状内皮系统刺激机制。
Br J Exp Pathol. 1970 Apr;51(2):140-8.
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Radiation and the phagocytic function of the reticuloendothelial system. I. Enhancement of RES function in x-irradiated mice.辐射与网状内皮系统的吞噬功能。I. X射线照射小鼠后网状内皮系统功能的增强
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Effects of carbon particles on phagocytic activity of reticuloendothelial system in X-irradiated mice.碳颗粒对受X射线照射小鼠网状内皮系统吞噬活性的影响。
J Radiat Res. 1974 Mar;15(1):14-8. doi: 10.1269/jrr.15.14.

本文引用的文献

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Effect of antibiotics on the phagocytic activity of the reticulo-endothelial system.
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The histopathology of bacterial infection in irradiated mice.辐照小鼠细菌感染的组织病理学
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8
The effect of strain and diet on the thirty-day mortality of x-irradiated germfree mice.应变和饮食对X射线照射的无菌小鼠30天死亡率的影响。
Radiat Res. 1966 Apr;27(4):616-29.

辐射与网状内皮系统的吞噬功能。II. 辐射后网状内皮系统刺激机制。

Radiation and the phagocytic function of the reticuloendothelial system. II. Mechanism of RES stimulation after irradiation.

作者信息

Sljivić V S

出版信息

Br J Exp Pathol. 1970 Apr;51(2):140-8.

PMID:4316098
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2072244/
Abstract

Treatment of mice with bone marrow or lymph-node cells or with antibiotics partially reversed the stimulating effect of irradiation on the phagocytic activity of the reticuloendothelial system (RES) as measured by the clearance of colloidal carbon from the blood. Irradiation of the rear part of the body, including the whole abdomen, resulted in a faster clearance of carbon, but irradiation of the front part of the body failed to do so. The phagocytic activity was not altered in irradiated germ-free mice, but was markedly enhanced in irradiated conventional and SPF animals. It was concluded that irradiation facilitates bacterial invasion which causes the stimulation of the RES.

摘要

用骨髓细胞、淋巴结细胞或抗生素处理小鼠，可部分逆转辐射对网状内皮系统（RES）吞噬活性的刺激作用，该作用通过血液中胶体碳的清除率来衡量。照射身体后部，包括整个腹部，会使碳的清除更快，但照射身体前部则不然。在经辐射的无菌小鼠中，吞噬活性没有改变，但在经辐射的普通和无特定病原体动物中，吞噬活性显著增强。得出的结论是，辐射促进细菌入侵，从而导致RES受到刺激。