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1
Lyophilization of cell-free Marek's disease herpesvirus and a herpesvirus from turkeys.无细胞马立克氏病疱疹病毒和一种来自火鸡的疱疹病毒的冻干处理
Appl Microbiol. 1970 Nov;20(5):723-6. doi: 10.1128/am.20.5.723-726.1970.
2
A comparison of the prophylactic efficacy of lyophilized and cell-associated turkey herpesvirus against Marek's disease.冻干型与细胞结合型火鸡疱疹病毒对马立克氏病预防效果的比较
Avian Dis. 1974 Jan-Mar;18(1):45-9.
3
Responses of cell cultures from various avian species to Marek's disease virus and herpesvirus of turkeys.不同禽类细胞培养物对马立克氏病病毒和火鸡疱疹病毒的反应。
Am J Vet Res. 1971 Nov;32(11):1811-23.
4
Trials with Marek's disease vaccines prepared from a turkey herpes virus and an attenuated Marek's disease virus.使用火鸡疱疹病毒和减毒马立克氏病病毒制备的马立克氏病疫苗的试验。
Vet Rec. 1975 Jul 19;97(3):50-2. doi: 10.1136/vr.97.3.50.
5
Characterization of a new serotype of Marek's disease herpesvirus.一种新型马立克氏病疱疹病毒血清型的鉴定
IARC Sci Publ (1971). 1975(11 Pt 2):329-36.
6
Marek's disease vaccine: prophylactic efficacy of a lyophilized turkey herpesvirus of chick cell-culture origin.马立克氏病疫苗：鸡胚细胞培养来源的冻干火鸡疱疹病毒的预防效果
Avian Dis. 1973 Jan-Mar;17(1):137-41.
7
Neutralization studies with Marek's disease virus and turkey herpesvirus.马立克氏病病毒和火鸡疱疹病毒的中和试验。
Appl Microbiol. 1973 Dec;26(6):925-33. doi: 10.1128/am.26.6.925-933.1973.
8
Efficacy of lyophilized turkey herpesvirus vaccine against Marek's disease in broilers.冻干火鸡疱疹病毒疫苗对肉鸡马立克氏病的疗效。
Poult Sci. 1975 Nov;54(6):1868-74. doi: 10.3382/ps.0541868.
9
Vaccination experiments against Marek's disease by application of an attenuated Marek herpesvirus and a turkey herpesvirus.应用减毒马立克氏疱疹病毒和火鸡疱疹病毒进行抗马立克氏病的疫苗接种实验。
Prog Immunobiol Stand. 1971;5:141-8.
10
Quantitative assay of turkey herpesvirus in vaccines against Marek's disease of chickens.鸡马立克氏病疫苗中禽疱疹病毒的定量测定。
Poult Sci. 1974 Nov;53(6):2153-8. doi: 10.3382/ps.0532153.

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Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine.开发稳健的冻干工艺以确保 rVSV-SARS-CoV-2 疫苗的长期稳定性。
Viruses. 2024 Jun 11;16(6):942. doi: 10.3390/v16060942.
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Vaccines against Major Poultry Viral Diseases: Strategies to Improve the Breadth and Protective Efficacy.重大禽类病毒性疾病疫苗：提高广度和保护效力的策略。
Viruses. 2022 May 31;14(6):1195. doi: 10.3390/v14061195.
3
The Leeuwenhoek Lecture, 1997. Marek's disease herpesvirus: oncogenesis and prevention.1997年列文虎克讲座。马立克氏病疱疹病毒：肿瘤发生与预防。
Philos Trans R Soc Lond B Biol Sci. 1997 Dec 29;352(1364):1951-62. doi: 10.1098/rstb.1997.0181.
4
Herpesvirus infection enhances cholesterol and cholesteryl ester accumulation in cultured arterial smooth muscle cells.疱疹病毒感染会增强培养的动脉平滑肌细胞中胆固醇和胆固醇酯的积累。
Am J Pathol. 1981 Nov;105(2):176-84.
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Immune response after exposure to varicella zoster virus: characterization of virus-specific antibodies and their corresponding antigens.接触水痘带状疱疹病毒后的免疫反应：病毒特异性抗体及其相应抗原的特征
Infect Immun. 1981 Jan;31(1):436-44. doi: 10.1128/iai.31.1.436-444.1981.
6
Neutralization studies with Marek's disease virus and turkey herpesvirus.马立克氏病病毒和火鸡疱疹病毒的中和试验。
Appl Microbiol. 1973 Dec;26(6):925-33. doi: 10.1128/am.26.6.925-933.1973.
7
Lyophilization of varicella virus. Brief report.
Arch Gesamte Virusforsch. 1973;40(3):397-9. doi: 10.1007/BF01242562.
8
An improved in vitro assay for cell-free Marek's disease virus. Brief report.一种改进的无细胞马立克氏病病毒体外检测方法。简报。
Arch Gesamte Virusforsch. 1971;34(4):391-5. doi: 10.1007/BF01242988.
9
Freeze-drying of respiratory syncytial viruses for transportation and storage.呼吸道合胞病毒的冻干用于运输和储存。
J Clin Microbiol. 1987 Sep;25(9):1769-71. doi: 10.1128/jcm.25.9.1769-1771.1987.
10
A comparison of the biological properties of type 2 plaque-producing agent derived from the Cal-1 strain of Marek's disease virus with other related viruses.源自马立克氏病病毒Cal-1株的2型致斑块剂与其他相关病毒生物学特性的比较。
Arch Virol. 1986;89(1-4):29-43. doi: 10.1007/BF01309877.

本文引用的文献

1
The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae.某些盐类、氨基酸、糖类及蛋白质对立克次氏体稳定性的影响。
J Bacteriol. 1950 Apr;59(4):509-22. doi: 10.1128/jb.59.4.509-522.1950.
2
A NEW MEMBER OF THE HERPESVIRUS GROUP ISOLATED FROM SOUTH AMERICAN MARMOSETS.从南美狨猴中分离出的疱疹病毒科新成员。
J Immunol. 1964 Apr;92:596-601.
3
Viral antigen, virus particles, and infectivity of tissues from chickens with Marek's disease.
J Natl Cancer Inst. 1970 Aug;45(2):341-51.
4
Feather follicle epithelium: a source of enveloped and infectious cell-free herpesvirus from Marek's disease.
Avian Dis. 1970 May;14(2):219-33.
5
Isolation from turkeys of a cell-associated herpesvirus antigenically related to Marek's disease virus.从火鸡中分离出一种与马立克氏病病毒抗原相关的细胞相关疱疹病毒。
Am J Vet Res. 1970 Mar;31(3):525-38.
6
Studies on acute Marek's disease. I. Characteristics of isolate GA in chickens.急性马立克氏病研究。I. 鸡体内分离株GA的特性
Avian Dis. 1968 Aug;12(3):467-76.

无细胞马立克氏病疱疹病毒和一种来自火鸡的疱疹病毒的冻干处理

Lyophilization of cell-free Marek's disease herpesvirus and a herpesvirus from turkeys.

作者信息

Calnek B W, Hitchner S B, Adldinger H K

出版信息

Appl Microbiol. 1970 Nov;20(5):723-6. doi: 10.1128/am.20.5.723-726.1970.

DOI:10.1128/am.20.5.723-726.1970
PMID:4320863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC377033/
Abstract

Cell extracts of the JM and GA strains of Marek's disease herpesvirus and the FC 126 strain of turkey herpesvirus were lyophilized with various stabilizers. Much higher virus titers were obtained with stabilizer than without stabilizer. Titers increased even further in the case of the Marek's disease virus strains by the addition of a chelating agent, disodium ethylenediaminetetraacetate.

摘要

马立克氏病疱疹病毒的JM和GA毒株以及火鸡疱疹病毒的FC 126毒株的细胞提取物用各种稳定剂进行冻干处理。使用稳定剂获得的病毒滴度比不使用稳定剂时高得多。对于马立克氏病病毒毒株，通过添加螯合剂乙二胺四乙酸二钠，滴度进一步提高。