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Homologies in amino acid composition and structure of histone F2al isolated from human leukaemic cells.

作者信息

Desai L S, Foley G E

出版信息

Biochem J. 1970 Sep;119(2):165-70. doi: 10.1042/bj1190165.

Abstract

Histones F2al extracted from normal and neoplastic cells possess similar amino acid compositions. Tryptic and chymotryptic peptides of the F2al histones have identical chromato-electrophoretic R(F) values. It is concluded that histones F2al from various sources have similar overall structures. The observed differences in the ratios of in-N-monomethyl- and di-in-N-methyl-lysine in the histones from normal and neoplastic cells may be of significance with respect to gene regulation.

摘要

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