内毒素休克中的血管活性激素：猫和狗的比较研究
Vasoactive hormones in endotoxin shock: a comparative study in cats and dogs.
作者信息
Hall R C, Hodge R L
出版信息
J Physiol. 1971 Feb;213(1):69-84. doi: 10.1113/jphysiol.1971.sp009368.
Abstract
- Entamoeba coli endotoxin was administered intravenously to cats and dogs.2. The changes in circulating levels of catecholamines and angiotensin following endotoxin were assayed by a continuous superfusion technique.3. The response of the dog was characterized by an immediate sustained rise in angiotensin levels and a later variable rise in catecholamine levels.4. The response of the cat was characterized by an early rise in catecholamine levels and a later rise in angiotensin levels.5. It is concluded that this species difference may reflect the relative importance of renin-angiotensin and sympatho-adrenal systems of dogs and cats, respectively.
摘要
将结肠内阿米巴内毒素静脉注射给猫和狗。
采用连续灌注技术测定内毒素作用后儿茶酚胺和血管紧张素循环水平的变化。
狗的反应特点是血管紧张素水平立即持续升高，随后儿茶酚胺水平有不同程度升高。
猫的反应特点是儿茶酚胺水平早期升高，随后血管紧张素水平升高。
得出的结论是，这种物种差异可能分别反映了狗和猫的肾素-血管紧张素系统和交感-肾上腺系统的相对重要性。
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本文引用的文献
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Studies on hemorrhagic and endotoxin shock in relation to vasomotor changes and endogenous circulating epinephrine, norepinephrine and serotonin.关于出血性休克和内毒素休克与血管运动变化以及内源性循环肾上腺素、去甲肾上腺素和血清素关系的研究。
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