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[特发性血色素沉着症的骨组织形态计量学与骨关节表现]

[Bone histomorphometry and osteo-articular manifestations of idiopathic hemochromatosis].

作者信息

Pawlotsky Y, Lancien Y, Roudier G, Hany Y, Louboutin J Y, Ferrand B, Bourel M

出版信息

Rev Rhum Mal Osteoartic. 1979 Feb;46(2):91-9.

PMID:432519
Abstract

An histomorphometric study of the bones was done on 28 patients suffering from an idiopathic hemochromatosis. There was a normocalcinemic hyperparathyroidism in half the cases. It appeared to be closely linked to hypersideremia and to be responsible for the sub-chondral arthropathy. The other lesions demonstrated were an osteoporous one, whose relations with hypogonadism was shown, and osteoidosis variations, which most often decreased rather than increased, and whose causes still seem uncertain.

摘要

对28例特发性血色素沉着症患者的骨骼进行了组织形态计量学研究。半数病例存在血钙正常的甲状旁腺功能亢进。它似乎与高铁血症密切相关,并导致软骨下关节病。其他表现出的病变包括骨质疏松,其与性腺功能减退的关系已得到证实,以及类骨质变化,这种变化大多是减少而非增加,其原因似乎仍不确定。

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