Bron B, Massih L, Brahime G, Obradovic D, Widgren S
Schweiz Med Wochenschr. 1979 Apr 21;109(16):610-2.
The diagnostic accuracy of endoscopic appearance, histology and brush cytology has been compared in a prospective study of 192 cases involving esogastric lesions. Macroscopic diagnosis of malignancy was more frequent in benign lesions (23/145) than in true malignancies (21/42). Histology was positive in 29/36 tumors and cytology in 23/36. In cytology there were no false negatives in esophageal tumors, but there were 52% false negatives in gastric tumors and 66% in carcinoma in situ. The combination of the 2 methods resulted in a correct diagnosis in 86% of the tumors in this study.
在一项对192例食管胃病变患者的前瞻性研究中，比较了内镜表现、组织学和刷检细胞学的诊断准确性。良性病变（23/145）中宏观诊断为恶性的情况比真正的恶性肿瘤（21/42）更常见。组织学检查在36例肿瘤中有29例呈阳性，细胞学检查在36例中有23例呈阳性。在细胞学检查中，食管肿瘤无假阴性，但胃肿瘤有52%的假阴性，原位癌有66%的假阴性。在本研究中，两种方法联合使用在86%的肿瘤中得出了正确诊断。
