Qizilbash A H, Castelli M, Kowalski M A, Churly A
Acta Cytol. 1980 Jul-Aug;24(4):313-8.
Brush cytology and biopsy under direct vision was performed on 250 patients. Of the 44 proven cases with cancers of the upper gastrointestinal tract, brush cytology yielded positive results in 88.6%, and multiple mucosal biopsies yielded positive results in 93.2%. With the combined technique the results increased to 95.4%. False-negative results were due to large tumors with necrotic surfaces or to infiltrative tumors at the cardioesophageal junction. There was one false positive with brush cytology and none with biopsy. Four cases of early gastric cancer were diagnosed with the combined technique.
对250例患者进行了刷片细胞学检查和直视下活检。在44例经证实的上消化道癌症病例中，刷片细胞学检查的阳性率为88.6%，多次黏膜活检的阳性率为93.2%。采用联合技术后，阳性率提高到95.4%。假阴性结果是由于肿瘤表面有坏死的大肿瘤或贲门食管交界处的浸润性肿瘤所致。刷片细胞学检查有1例假阳性，活检无假阳性。联合技术诊断出4例早期胃癌。
