Umanskiĭ Iu A, Evsev'eva A I, Semenova-Kobzar' R A, Kushko L Ia
Tsitologiia. 1979 Feb;21(2):191-5.
A study was made of the PHA-induced lymphocyte blastransformation (BT), and lymphocyte antitumor activity, using a model of progressive and regressive neoplastic process induced by the Moloney virus in mice BALB/c. The antitumor acitvity of lymphocytes was estimated by their ability to inhibit spheroid production by tumor cells. A lymphocyte BT and their antitumor activity was registered during a progressive growth of the tumor and its restoration as the tumor is regressing.