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[肺癌、良性肿瘤及慢性非特异性肺炎中的止血系统]

[Hemostasis system in lung cancer, benign tumors and chronic nonspecific pneumonias].

作者信息

Shilov N I

出版信息

Vopr Onkol. 1979;25(4):21-5.

PMID:433213
Abstract

A comparative study, condicted on the coagulation status, indicated that tumor and chronic inflammatory processes in the lung as associated with high blood content of fibrinogen and fibrinogen B, the increased plasma tolerance to heparin and degree of thrombotest with a compensatory increase of the heparin content and antithrombin activity. Lung tumor patients contrary to patients with pneumonias showed a high thromboplastin activity and reduced fibrinolysis indices. The activation of euglobulin fibrinolysis is characteristic of the hemostasis system in patients with chronic pneumonias. The revealed alterations may be used both for timely prophylaxis of coagulopathy and as an adjuvant method in the differential diagnosis.

摘要

一项关于凝血状态的对比研究表明,肺部的肿瘤和慢性炎症过程与血液中纤维蛋白原和纤维蛋白原B含量高、血浆对肝素的耐受性增加、凝血酶试验程度增加以及肝素含量和抗凝血酶活性的代偿性增加有关。与肺炎患者相反,肺癌患者表现出高凝血活酶活性和降低的纤维蛋白溶解指标。优球蛋白纤维蛋白溶解的激活是慢性肺炎患者止血系统的特征。所揭示的这些变化可用于及时预防凝血病,也可作为鉴别诊断的辅助方法。

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