血管紧张素拮抗剂。在第8位将苯环上的脂肪链进行取代。 - Suppr

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超能文献

Antagonists of angiotensin. Substitution of an aliphatic chain to phenyl ring in position 8.

作者信息

Regoli D, Park W K, Rioux F, Chan C S

出版信息

Rev Can Biol. 1971 Dec;30(4):319-29.

PMID:4332582

Abstract

摘要

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A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin II.天冬氨酸1-异亮氨酸5-血管紧张素II的两种结构相关类似物的比较研究。

Naunyn Schmiedebergs Arch Pharmacol. 1974;282(4):411-20. doi: 10.1007/BF00500989.

Characterization of angiotensin receptors in vascular and intestinal smooth muscles.血管和肠道平滑肌中血管紧张素受体的特征

Br J Pharmacol. 1973 Jun;48(2):288-301. doi: 10.1111/j.1476-5381.1973.tb06915.x.

Blockade and stimulation of renal, adrenal, and vascular angiotensin II receptors with 1-Sar, 8-Ala angiotensin II in normal man.在正常男性中用1- Sar，8- Ala血管紧张素II阻断和刺激肾、肾上腺及血管的血管紧张素II受体。

J Clin Invest. 1976 Jan;57(1):39-46. doi: 10.1172/JCI108266.

Angiotensin antagonists with increased specificity for the renal vasculature.对肾血管系统具有更高特异性的血管紧张素拮抗剂。

J Clin Invest. 1977 Mar;59(3):528-35. doi: 10.1172/JCI108668.

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