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不饱和脂肪酸对酿酒酵母不饱和脂肪酸突变体呼吸发育及蛋白质合成的影响。

Effect of unsaturated fatty acids on the development of respiration and on protein synthesis in an unsaturated fatty acid mutant of Saccharomyces cerevisiae.

作者信息

Gordon P A, Lowdon M J, Stewart P R

出版信息

J Bacteriol. 1972 May;110(2):511-5. doi: 10.1128/jb.110.2.511-515.1972.

Abstract

The extent of development of respiratory function induced by aeration of an anaerobically grown unsaturated fatty acid auxotroph of Saccharomyces cerevisiae is determined by the availability, endogenous or externally supplied, of unsaturated fatty acid. The synthesis of mitochondrial and cytoplasmic enzymes during aeration appears to have a similar basis of regulation by available unsaturated fatty acid. Levels of unsaturated fatty acid that permit the synthesis of mitochondrial enzymes also result in a substantial stimulation of cellular protein synthesis.

摘要

通过对酿酒酵母厌氧生长的不饱和脂肪酸营养缺陷型进行通气处理所诱导的呼吸功能发育程度,取决于不饱和脂肪酸的可获得性,无论是内源性的还是外部供应的。通气过程中线粒体和细胞质酶的合成似乎有着类似的由可获得的不饱和脂肪酸进行调控的基础。允许线粒体酶合成的不饱和脂肪酸水平也会显著刺激细胞蛋白质合成。

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本文引用的文献

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Fatty acid desaturase mutants of Saccharomyces cerevisiae.
J Bacteriol. 1969 May;98(2):415-20. doi: 10.1128/jb.98.2.415-420.1969.
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Mitochondrial membrane organisation, a determinant of mitochondrial ribosomal RNA synthesis.
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