长期使用皮质类固醇治疗期间肾上腺皮质功能的恢复
Recovery of adrenocortical function during long-term treatment with corticosteroids.
作者信息
Westerhof L, Van Ditmars M J, Der Kinderen P J, Thijssen J H, Schwarz F
出版信息
Br Med J. 1972 Apr 22;2(5807):195-7. doi: 10.1136/bmj.2.5807.195.
Abstract
The recovery of adrenocortical function during long-term corticosteroid treatment in a group of patients with asthmatic bronchitis was compared with that in a group of patients with sarcoidosis. At corresponding dosages of prednisone basal adrenocortical function as well as adrenocortical response to tetracosactrin stimulation was higher in the asthma patients than in those with sarcoidosis.The rate of recovery of adrenocortical function seems mainly to be determined by the dosage of corticosteroids during the initial stages of treatment rather than by the nature of the disease.
摘要
将一组哮喘性支气管炎患者与一组结节病患者在长期使用皮质类固醇治疗期间肾上腺皮质功能的恢复情况进行了比较。在泼尼松剂量相当的情况下，哮喘患者的基础肾上腺皮质功能以及对二十四肽促皮质素刺激的肾上腺皮质反应均高于结节病患者。肾上腺皮质功能的恢复速率似乎主要取决于治疗初始阶段皮质类固醇的剂量，而非疾病的性质。
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本文引用的文献
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Adrenal function after prolonged corticosteroid therapy.长期皮质类固醇治疗后的肾上腺功能。
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STUDIES OF ADRENOCORTICAL FUNCTION IN CONTINUOUS ASTHMA.持续性哮喘患者肾上腺皮质功能的研究
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NATURAL HISTORY OF PITUITARY-ADRENAL RECOVERY FOLLOWING LONG-TERM SUPPRESSION WITH CORTICOSTEROIDS.长期使用皮质类固醇抑制后垂体 - 肾上腺恢复的自然史
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