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马流产(疱疹)病毒:二硫苏糖醇对其灭活敏感性的毒株差异

Equine abortion (herpes) virus: strain differences in susceptibility to inactivation by dithiothreitol.

作者信息

Klingeborn B, Dinter Z

出版信息

Appl Microbiol. 1972 Jun;23(6):1121-4. doi: 10.1128/am.23.6.1121-1124.1972.

Abstract

The infectivity of equine abortion (herpes) virus (EAV) was inactivated by treatment with reduced dithiothreitol (DTT). According to their susceptibility to DTT, the EAV strains could be divided into three groups. The vaccine strain RAC-H (419) proved to be more resistant to DTT than all of the other 14 strains tested. The hemagglutinin of EAV was also inactivated by DTT; no strain differences were observed in this respect.

摘要

用还原型二硫苏糖醇(DTT)处理可使马流产(疱疹)病毒(EAV)的传染性失活。根据EAV毒株对DTT的敏感性,可将其分为三组。疫苗株RAC-H(419)对DTT的抗性比其他所有测试的14个毒株都更强。EAV的血凝素也被DTT失活;在这方面未观察到毒株差异。

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本文引用的文献

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Differentiation of equine herpesvirus type I strains by a plaque marker. Brief report.
Arch Gesamte Virusforsch. 1970;32(2):283-5. doi: 10.1007/BF01249964.
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Equine herpesvirus type 1: the L- character in two of forty-three field isolates. Brief report.
Arch Gesamte Virusforsch. 1972;36(3):391-3. doi: 10.1007/BF01249870.
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Viral inactivation by disulfide bond reducing agents.二硫键还原剂对病毒的灭活作用。
J Virol. 1968 Dec;2(12):1482-4. doi: 10.1128/JVI.2.12.1482-1484.1968.
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Role of hydrogen and disulfide bonds in polyoma capsid structure.
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