Sato K, Morris H P, Weinhouse S
Science. 1972 Nov 24;178(4063):879-81. doi: 10.1126/science.178.4063.879.
A third set of phosphorylase a and b isozymes, distinguishable kinetically and immunologically from liver and muscle forms, is present in various rat hepatomas, and is also present, together with the adult liver form, in fetal rat liver. This is one of several striking examples of suppression of isozymes of adult liver coupled with the appearance of fetal isozymes in hepatomas.
第三组磷酸化酶a和b同工酶,在动力学和免疫学上与肝脏和肌肉中的形式不同,存在于各种大鼠肝癌中,并且与成年肝脏形式一起也存在于胎鼠肝脏中。这是成年肝脏同工酶受抑制同时肝癌中出现胎儿同工酶的几个显著例子之一。